منابع مشابه
Duty ratio of cooperative molecular motors
Motor proteins are specialized molecules that convert chemical energy into useful mechanical work and govern many important biological processes. They bind to actin filaments and microtubules and use them as tracks, on which they propagate in order to transport different types of cargo across the cell. Among these molecules we find myosin II motors that interact with elastic actin filaments. My...
متن کاملDuty ratio of cooperative molecular motors.
Molecular motors are found throughout the cells of the human body and have many different and important roles. These micromachines move along filament tracks and have the ability to convert chemical energy into mechanical work that powers cellular motility. Different types of motors are characterized by different duty ratios, which is the fraction of time that a motor is attached to its filamen...
متن کاملBidirectional cooperative motion of molecular motors.
Recently, in a beautiful set of experiments, it has been shown that a Ncd mutant, NK11, which lacks directionality in its individual motion, was able to exhibit a new kind of directed motion in motility assays (Endow, S. A. & Higuchi, H. (2000) Nature (London) 406, 913-916): the filaments keep a given velocity for a while and then suddenly move in the opposite direction with similar velocity. W...
متن کاملCooperative molecular motors moving back and forth.
We use a two-state ratchet model to study the cooperative bidirectional motion of molecular motors on cytoskeletal tracks with randomly alternating polarities. Our model is based on a previously proposed model [Badoual, Proc. Natl. Acad. Sci. U.S.A. 99, 6696 (2002)] for collective motor dynamics and, in addition, takes into account the cooperativity effect arising from the elastic tension that ...
متن کاملCooperative cargo transport by several molecular motors.
The transport of cargo particles that are pulled by several molecular motors in a cooperative manner is studied theoretically in this article. The transport properties depend primarily on the maximal number N of motor molecules that may pull simultaneously on the cargo particle. Because each motor must unbind from the filament after a finite number of steps but can also rebind to it again, the ...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2012
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.85.021904